IndraLab

Statements

CACNA1A activates tDLN. 5 / 5
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"B/I activated tDLN demonstrate increased expression of message for cytolytic mediators."
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"Adoptive transfer of B/I activated tDLN was effective at inducing 4T1 tumor regression in nude mice pre-treated with CYP but IL-2 was neither beneficial nor required (data not shown, [F (2,13) = 11.289, P = 0.0014])."
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"One of the key potential advantages of B/I activation of tDLN is the ability of these cells to continue proliferating in adoptive hosts after AIT, without the need for exogenous cytokines or antigen vaccination."
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"B/I activated tDLN release IFN-gamma in response to tumor challenge."
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"To ascertain whether the proliferation we observed in vivo for B/I activated tDLN in TBH mice resulted simply from homeostatic proliferation after the CYP treatment or is enhanced by the prior B/I stimulation, freshly harvested tDLN were transferred into CYP pre-treated TBH mice and B/I activated tDLN were infused into similar hosts, with or without CYP pre-treatment."
21050466