IndraLab

Statements

TCF7L2 binds KCNQ1. 2 / 2
| 1 1
sparser
"Of these, 8 SNPs including IGF2BP2 rs4402960, WFS1 rs734312, CDKAL1 rs7756992, SLC30A8 rs13266634, CDKN2A/B rs10811661, HHEX rs7923837, TCF7L2 rs7903146 and KCNQ1 rs2237892 were consistently and significantly associated with T2D after adjusting for sex, age and BMI (OR = 1.14–2.09, 8.5×10 −18 < P <8.5×10 −3 ) ( xref )."
24376643
reach
"Besides, the authors identified 1,649 CpG sites and 853 genes in T2D islets with changes in the DNA methylation level, including fat mass and obesity-associated (FTO), potassium voltage-gated channel subfamily Q member 1 (KCNQ1), and transcription factor-7-like-2 (TCF7L2)."
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