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BAP1 inhibits dedifferentiation. 2 / 2

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"Loss of BAP1 induces dedifferentiation of melanoma cells and the development of stem cell like characteristics XREF_BIBR, XREF_BIBR."

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"The recent finding that BAP1 loss leads to defective differentiation and an arrested primitive phenotype in vertebrate development and uveal melanoma suggests that BAP1 loss can promote tumor progression by inducing cell dedifferentiation and stem like behavior."

32690542

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IndraLab

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BAP1 inhibits dedifferentiation. 2 / 2

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