IndraLab

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FN1 activates ITGB1 bound to ITGA5. 1 / 1

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"We have developed a cell-free assay for binding of solubilized beta1 integrins to their physiologically relevant ligands using an electrochemiluminescent detection method|Binding was clearly optimal for the presumed physiological ligands, i.e., collagen IV for a1b1, collagen I for a2b1, VCAM-Ig for a4b1, fibronectin (the 120-kDa cell attachment fragment was used) for a5b1, and laminin for a6b1."

12123670

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IndraLab

Statements

FN1 activates ITGB1 bound to ITGA5. 1 / 1

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