IndraLab

Statements


CACNA1C activates RBM20. 2 / 2
| 2

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"On the other hand, splicing alterations in other RBM20 targets such as CamkIIdelta, RyR2, and Cacna1c might affect Ca 2+ homeostasis."

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"Genome editing studies show that TTN pre-mRNA, the main RBM20 regulated transcript in the heart, nucleates RBM20 foci that drive spatial proximity between the TTN locus and other inter-chromosomal RBM20 targets such as CACNA1C and CAMK2D."