IndraLab

Statements

TBK1 binds USP24. 8 / 8
1 | 7
biogrid
No evidence text available
36334706
sparser
"Our above studies have demonstrated that USP24 interacts with TBK1."
36334706
sparser
"We found that USP24 could interact with TBK1, but not RIG-I, MAVS, TRAF6/3, or IRF3 ( xref A–F)."
36334706
sparser
"Furthermore, we confirmed that endogenous TBK1 could interact with endogenous USP24 in HEK293T cells ( xref G)."
36334706
sparser
"USP24 interacts with TBK1 to reduce the K63-linked polyubiquitination of TBK1, thereby affecting IRF3 activation and IFN-I production [ xref ]."
38674024
sparser
"Further studies revealed that USP24 physically interacted with TBK1, and can reduce K63-linked polyubiquitination of TBK1."
36334706
sparser
"Thus, this study revealed the regulation of the USP24-TBK1 axis on EV71 infection."
36334706
sparser
"USP24 can interact with TBK1."
36334706