IndraLab

Statements

OTUD7B activates H3K4me2. 2 / 2
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"The fact that many of these gene hits are linked to cell cycle likely explains the result that the primary functions of OTUD7B or LSD1 in coordinating cell cycle progression.The above ChIP‐seq and RNA‐seq datasets were aligned to explore the potential correlations between OTUD7B‐induced H3K4me2 and LSD1 occupancy changes and changes in gene transcription."
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reach
"Importantly, in LSD1‐reconstituted cells, LSD1 rendered their promoters resistant to OTUD7B ablation‐induced H3K4me2/H3K9me2 alterations (Figure 6J,L)."
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