IndraLab

Statements


| 4

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"Based on the results, we conclude that the intact catalytic triad of TGEV PL1 is required to inhibit activation of the IFN-β promoter driven by STING and TBK-1."

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"Based on the results, we conclude that the intact catalytic triad of TGEV PL1 is required to inhibit activation of the IFN-beta promoter driven by STING and TBK-1."

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"Previous studies have shown that HP-PRRSV-nsp4 inhibits IFN-I production induced by poly (I : C) and the catalytic triad His39-Asp64-Ser118 is essential for nsp4 to block IFN-beta production."
| PMC

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"As such, APAP is more likely to lower the efficacy of IFN-β treatment as opposed to abrogate a desired endpoint."