IndraLab

Statements


STAMBP inhibits SMAD6. 3 / 3
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"Smad6 can be sequestered by the protein AMSH upon nuclear export in response to BMP (Itoh et al., 2001)."

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"AMSH has been reported to antagonise Smad6 function, and promote BMP signalling."

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"It has been proposed that AMSH sequesters SMAD6, thus impeding its inhibitory role on the BMP pathway and thereby resulting in a prolonged BMP signalling."