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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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Statements

STAMBP inhibits SMAD6. 3 / 3

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"Smad6 can be sequestered by the protein AMSH upon nuclear export in response to BMP (Itoh et al., 2001)."

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"AMSH has been reported to antagonise Smad6 function, and promote BMP signalling."

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"It has been proposed that AMSH sequesters SMAD6, thus impeding its inhibitory role on the BMP pathway and thereby resulting in a prolonged BMP signalling."

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INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...

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Statements

STAMBP inhibits SMAD6. 3 / 3

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