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Statements

YOD1 activates Mice. 2 / 2
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"Thus, both morphological analysis and proportion of hCD45 mCD45 demonstrate that YOD1 knockdown reduces the human APL burden in leukemic mice."
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"Interestingly, in sharp contrast to the finding that colitis induced the overall downregulation of YOD1 in colon tissue, YOD1 expression was upregulated in colon-infiltrating macrophages in both mice and humans during colitis (Fig. 3A,B; Appendix Fig. S6)."
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