IndraLab

Statements


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"In the resected tumor tissues, the miR-216b-overexpressed tumors expressed obviously lower level of c-Jun and Bcl-xl compared to the control tumors after they were treated with equal dose of cisplatin."

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"Cisplatin treatment decreased ERK-, JNK- and c-Jun activity in alpha-catulin knockdown melanoma cells, which was accompanied by reduced cell proliferation and enhanced apoptosis compared to control cells."

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"Moreover, PDIA6 suppressed cisplatin-induced NSCLC cell apoptosis and autophagy through interacting with MAP4K1 to inhibit the JNK/c-Jun signaling pathway."