IndraLab

Statements

USP7 leads to the deubiquitination of ARMC5. 3 / 3
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"Silencing of USP7 enhanced ARMC5 ubiquitination and accelerated cell cycle G1/S, subsequently promoted RCC cell proliferation."
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"Conversely, overexpression of USP7, but not its catalytically mutant, reversed ARMC5 ubiquitination levels."
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"Silencing of USP7 decreased ARMC5 levels, accompanied by increasing ARMC5 polyubiquitination, whereas overexpression of USP7 but not its mutants increased ARMC5 levels and reversed ARMC5 polyubiquitination."
33544460