IndraLab

Statements

Auranofin inhibits CTSB. 4 / 4
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"Auranofin also inhibits mitochondrial thioredoxin reductase (TrxR) [XREF_BIBR] and cathepsin B [XREF_BIBR]."
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"AF also inhibits cathepsin B ( Gunatilleke et al., 2008; Kast, 2010 ), which has been shown to be one of the neurotoxins secreted by glial cells ( Kingham and Pocock, 2001 )."
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"Auranofin inhibits cathepsin B and was previously suggested as a glioblastoma treatment adjunct on that basis [XREF_BIBR]."
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"AF also inhibits cathepsin B ( Gunatilleke et al., 2008; Kast, 2010 ), which has been shown to be one of the neurotoxins secreted by glial cells ( Kingham and Pocock, 2001 )."
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