IndraLab

Statements

RA-9 inhibits UCHL3. 4 / 4
| 4
reach
"AM146, RA-9, and RA-14 were found to inhibit UCHL1, UCHL3, USP2 and USP8, but did not suppress the activity of Ataxin-3, A20, BAP1, Otubain 1 or USP7 ( Issaenko & Amerik, 2012 )."
25444757
reach
"Additionally, chalcone-based derivatives AM146, RA-9 and RA-14, which contain α,β-unsaturated carbonyl groups, directly target and suppress the activity of UCH-L1, UCH-L3, USP2, USP5 and USP8 without [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
24534329
reach
"RA-9, a chalcone derivative with a structure similar to b-AP15, was reported to inhibit proteasomal DUBs [XREF_BIBR] as well as UCHL1, UCHL3, USP2, USP5, and USP8 [XREF_BIBR]."
29039082
reach
"Indeed, it was found that RA-9 inhibited in vitro UCHL1, UCHL3, USP8 and USP9x, besides USP14 and UCHL5."
27381943