IndraLab

Statements


USP25 inhibits IL17A. 5 / 5
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reach
"In this study, we found that overexpression of USP25 negatively regulated IL-17- but not TNF triggered signaling."

reach
"Targeting USP25 may modulate responses to IL-17, and could be beneficial in certain types of infections and cancers."

reach
"These results indicate that USP25 restricts IL17 mediated pulmonary inflammation in vivo."

reach
"These data together suggest that USP25 restricts IL-17 and IL-17F signaling in various types of cells."

sparser
"Real-time RT-PCR analysis showed that overexpression of USP25 inhibited IL-17- but not TNF-induced expression of Cxcl1 and Il6 mRNA in HeLa cells and in 293T-IL-17RA/C cells ( xref and xref )."