IndraLab

Statements


ZRANB1 inhibits HYCC1. 2 / 2
| 2

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"However, the function of RNF8 in hepatocellular tumorigenesis remains unknown despite reports that RNF8-induced K63 ubiquitination of Twist1 is involved in the trabid-mediated inhibition of HCC growth and metastasis [20]."

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"More importantly, ZRANB1 regulated LOXL2 through specificity protein 1 (SP1) and SP1 overexpression rescued the suppression of HCC growth and metastasis induced by ZRANB1 knockdown."