IndraLab

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"NICD subsequently migrates into the nucleus and binds to the transcription factor CBF-1 and RBP-J, Su (H), Lag-1 (CSL), which in Drosophila melanogaster is known as Suppressor of Hairless, or Su (H) (see also XREF_FIG)."

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"In the nucleus, NICD interacts with LAG-1 and LAG-3 (a homolog of mastermind transcriptional co-activators) to activate the expression of Notch target genes (XREF_FIG A)."