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USP15 bound to MDM2 activates TCR. 1 / 1

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"First, USP15 interacts with MDM2, inhibits ubiquitination, and stabilizes MDM2, an important E3 ligase that mediates the ubiquitination and proteolysis of NFATc2 members of the NFAT family and negatively regulates TCR signals."

32850399

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IndraLab

Statements

USP15 bound to MDM2 activates TCR. 1 / 1

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