IndraLab

Statements

USP10 activates CAPRIN1. 2 / 2
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"G3BP-binding and SG-inhibiting variants of USP10 and SFV-nsP3 (XREF_FIG, lanes 3, 5, 6, and 8) selectively decrease G3BP1/2 and Caprin1 B-isox precipitation without affecting that of TIA-1, TIAR, TDP43, or PABP."
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"Interestingly, our previous map of human protein complexes (Drew et al., 2017a) suggests that the known complex of G3BP, CAPRIN, and USP10 (Kedersha et al., 2016) also physically interacts with NUFIP2, leading us to suggest the name CapGUN (i.e., CAPRIN1, G3BP2, USP10, NUFIP2)."
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