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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

USP10 activates CAPRIN1. 2 / 2

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"G3BP-binding and SG-inhibiting variants of USP10 and SFV-nsP3 (XREF_FIG, lanes 3, 5, 6, and 8) selectively decrease G3BP1/2 and Caprin1 B-isox precipitation without affecting that of TIA-1, TIAR, TDP43, or PABP."

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"Interestingly, our previous map of human protein complexes (Drew et al., 2017a) suggests that the known complex of G3BP, CAPRIN, and USP10 (Kedersha et al., 2016) also physically interacts with NUFIP2, leading us to suggest the name CapGUN (i.e., CAPRIN1, G3BP2, USP10, NUFIP2)."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...