IndraLab

Statements

OTUD7A binds KDM5B. 2 / 2
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"This discovery aligns with recent studies on the involvement of epigenetic regulators in ferroptosis [ xref , xref – xref ], but innovatively defines the OTUD7A-KDM5B axis as a direct bridge linking the regulation of protein stability to histone modification, thereby precisely controlling the ferroptosis process."
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"Co-IP experiments performed in SW1573, A549, and 293T cell lines, as well as immunofluorescence co-localization experiments in SW1573 and A549 cell lines, demonstrated a significant interaction between OTUD7A and KDM5B (Figs. xref and xref )."
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