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BRCA1 activates BRCC3. 2 / 2

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"The experiments were performed in triplicates comparing the cells treated with siRNAs against BRCC36 or BRE, to those treated with siRNAs against BRCA1 and control siRNAs."

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reach

"Recent studies have shown that specific phosphorylation of NLRP3 by c-Jun N-terminal Protein Kinase 1 (JNK1) can lead to activation of NLRP3 as a result of deubiquitylation by BRCA1/BRCA2-containing complex 3 (BRCC3), a component of the cytosolic BRISC complex (BRCC3 isopeptidase complex)."

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IndraLab

Statements

BRCA1 activates BRCC3. 2 / 2

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