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USP11 activates cellular senescence. 2 / 2

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"Previously, we showed that USP11 knock-down in HDFs induces senescence [XREF_BIBR], here we report that USP11 ablation in U2OS cells results in multipolar spindle formation with an increased number of multinucleated cells."

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"USP11 modulates mitotic progression and senescence by regulating the p53-p21 axis through MDM2 deubiquitination."

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USP11 activates cellular senescence. 2 / 2

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