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USP7 activates cell. 2 / 2
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eidos
"We also observed that loss of USP7 led to reduced cell proliferation and increased population of G2 phase cells ( Supplementary Fig. S2f ) , consistent with an increased p21 expression ."

eidos
"For example , USP7 stabilizes the p53 protein to act as a tumor suppressor ( Li et al ., 2002 ) but promotes the proliferation of HCC cells via deubiquitination of YAP ( Sun et al ., 2019 ) ."