IndraLab

Statements

COPS6 increases the amount of FOXA1. 3 / 3
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"Silencing CSN6 caused a decrease of mRNA and protein expression of FOXA1, and overexpression of CSN6 upregulated mRNA and protein expression of FOXA1 ( Fig. 3 a and b)."
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"The result showed that inhibition of CSN6 suppressed protein expression of c-Fos but had no influence on mRNA expression of c-Fos, and decreased mRNA and protein expression of FOXA1 ( Fig. 5 a and b)."
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"Overexpression of CSN6 could upregulate c-Fos protein thereby enhancing AP-1 transcriptional activity to promote mRNA expression of FOXA1 ( Fig. 5 )."
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