IndraLab

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"Ginsenoside Rb1 and compound K also significantly inhibited the activation of interleukin-1 receptor associated kinase-1 (IRAK-1), IKK-beta, NF-kappaB, and MAP kinases (ERK, JNK, and p-38); however, interaction between LPS and Toll like receptor-4, IRAK-4 activation and IRAK-2 activation were unaffected."

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"Ginsenoside Rb1 and its metabolite compound inhibited the activation of key inflammatory mediators IRAK-1 (interleukin-1 receptor associated kinase-1), IKK-beta (inhibitor of NF-kappabeta kinase), NF-kappabeta, and MAPK (mitogen activated protein kinases) while suppressing colitis [XREF_BIBR]."