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USP18 activates EGF. 1 / 1
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"In addition, the results indicated that USP18 may promote the epidermal growth factor (EGF)-mediated EGF receptor (EGFR)/AKT/S-phase kinase associated protein2 (Skp2) pathway by upregulating EGFR and Skp2 in a AKT and forkhead boxO3 dependent manner in breast cancer."