IndraLab

Statements

REST inhibits HCN4. 3 / 3
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"In another set of experiments, we examined cardiac expression of the NRSF, which may repress HCN4 gene activity in cardiomyocytes [XREF_BIBR]."
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"A functional NRSF binding site was identified in the Hcn4 promotor, and a promotor activity study revealed that NRSF represses Hcn4 promoter activity [ 27 ]."
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"During embryonic heart development, the elevated REST inhibited an embryonic cardiac gene HCN4 [ xref , xref , xref , xref ]."
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