IndraLab

Statements

Ethanol inhibits CTSB. 8 / 8
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"Though ethanol inhibited neither cathepsin B, cathepsin D, nor chymotrypsin-like activity, it did significantly reduce calpain I expression and activity."
18672021
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"In the present study ethanol significantly reduced the cholesterol crystal induced secretion of IL-1beta, and moreover, ethanol also inhibited lysosomal disruption, and the release of cathepsin B (XREF_FIG)."
24244322
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"In corroboration with our results, Hirano and Manabe demonstrated that ethanol consumption causes a significant decrease of cathepsin B activity in the pancre- atic lysosomal fraction."
8781524
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"Moreover, alcohol fed mice also had decreased cathepsin B activities in mouse pancreas compared with control diet fed mice (XREF_FIG F)."
31987928
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"Gallic acid especially at 200 mg/kg improved ethanol mediated pancreatic tissue damage.In conclusion, gallic acid treatments were decreased release of lysosomal cathepsin B and L enzymes into cytoplasmic fraction and prevented alcohol mediated pancreatic tissue injury."
23053933
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"In line with the above described studies with acridine orange, ethanol inhibited the cholesterol crystal induced leakage of cathepsin B into the cytoplasm."
24244322
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"Although neither cathepsin B, cathepsin D nor chymotrypsin like activity were inhibited by ethanol (data not shown), ethanol did reduce calpain activity consistent with the finding that ethanol inhibits calpain activity in PC12 cells [XREF_BIBR]."
18672021
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"Our findings suggest that ethanol consumption impaired the biosynthesis of cathepsin B, as indicated by lower quantities and activities of this protease in both post-nuclear and lysosome fractions of [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
8541322