IndraLab

Statements

KCNE5 activates KCNQ1. 3 / 3
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"It does this without reducing the surface expression of KCNQ1 XREF_BIBR, XREF_BIBR, although it has been reported that KCNE4 (and KCNE5) prevent targeting of KCNQ1 to lipid rafts 53; KCNE4-KCNQ1 complexes are detectable in the plasma membrane when the two are co-expressed 51."
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"KCNE5 induces time- and voltage dependent modulation of the KCNQ1 current."
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"It does this without reducing the surface expression of KCNQ1 (Grunnet et al., 2002; Grunnet et al., 2005), although it has been reported that KCNE4 (and KCNE5) prevent targeting of KCNQ1 to lipid raf[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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