IndraLab

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OTUD4 activates TGFB. 3 / 3
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"OTUD4 enhances TGFbeta signalling through regulation of the TGFbeta receptor complex."
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"Specifically , we find that OTUD4 enhances TGFbeta signalling by promoting the membrane presence of TGFbeta receptor I. Furthermore , we demonstrate that OTUD4 inactivates the TGFbeta negative regulator SMURF2 suggesting that OTUD4 regulates multiple nodes of the TGFbeta pathway to enhance TGFbeta activity ."
32973272
eidos
"OTUD4 enhances TGFbeta signalling through regulation of the TGFbeta receptor complex ."
32973272