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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

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INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

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OTUD4 activates TGFB. 3 / 3

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"OTUD4 enhances TGFbeta signalling through regulation of the TGFbeta receptor complex."

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"Specifically , we find that OTUD4 enhances TGFbeta signalling by promoting the membrane presence of TGFbeta receptor I. Furthermore , we demonstrate that OTUD4 inactivates the TGFbeta negative regulator SMURF2 suggesting that OTUD4 regulates multiple nodes of the TGFbeta pathway to enhance TGFbeta activity ."

32973272

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eidos

"OTUD4 enhances TGFbeta signalling through regulation of the TGFbeta receptor complex ."

32973272

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OTUD4 activates TGFB. 3 / 3

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