IndraLab

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UCHL1 activates MITF. 2 / 2
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"UCHL1 downregulation by small interfering RNA resulted in upregulation of microphthalmia associated transcription factor (MITF), tyrosinase, dopachrome tautomerase, tyrosinase related protein-1, and melanin."

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"These results indicated that UCHL1 negatively influenced the stability of MITF protein.We next investigated the potential molecular mechanism underlying the observed downregulation of MITF protein ind[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"