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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

UCHL1 activates MITF. 2 / 2

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"UCHL1 downregulation by small interfering RNA resulted in upregulation of microphthalmia associated transcription factor (MITF), tyrosinase, dopachrome tautomerase, tyrosinase related protein-1, and melanin."

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"These results indicated that UCHL1 negatively influenced the stability of MITF protein.We next investigated the potential molecular mechanism underlying the observed downregulation of MITF protein ind[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...