IndraLab

Statements

Ubiquitin activates USP7. 4 / 4
| 4
reach
"It shows that ubiquitin trapped in the active site of USP7 causes rearrangements of the catalytic triad and the adjacent " switching " loop of USP7."
30807924
reach
"Binding of Ub triggers a drastic conformational change in the active site of HAUSP that realigns the catalytic triad for specific catalysis on the C-terminal di-glycine motif of Ub 36."
28536428
reach
"Taking these data together, USP7 beta represents a higher MW species of USP7 that shares significant amino acid homology.ICP0 can catalyse the ubiquitination of USP7 (Boutell et al., 2005), suggesting[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
18590780
reach
"TP53 Ub-ID lead to low number but consistent identifications (Fig. 9c): PCNA, BCOR, RNF20, RNF40, RNF220, RFC4, the Ub E1 activating enzyme UBA1 and the deubiquitylating enzyme USP7."
34795231