IndraLab

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KCNMA1 activates TICAM2. 1 / 1
| 1

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"SLO, binding to TLR4, activates the TRIF- and MyD88-dependent signalling pathway, which by inducing p38 MAPK activation, provokes the phosphorylation of cPLA 2 , which in turn provides the arachidonic acid to be oxidized by 5-LO, thereby activating the cascade leading to CysLTs production."