IndraLab
Statements
sparser
"SLO, binding to TLR4, activates the TRIF- and MyD88-dependent signalling pathway, which by inducing p38 MAPK activation, provokes the phosphorylation of cPLA 2 , which in turn provides the arachidonic acid to be oxidized by 5-LO, thereby activating the cascade leading to CysLTs production."