IndraLab

Statements

Pentamidine activates KCNH2. 8 / 8
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"Dofetilide corrected pentamidine induced hERG, but not K (IR) 2.1 trafficking defects."
23586323
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"Pentamidine induced long QT syndrome and block of hERG trafficking."
21228407
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"Pentamidine induced long QT syndrome and block of hERG trafficking."
15340016
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"The high-affinity drug binding site Phe656 of the hERG channel is essential for intracellular pentamidine interaction, which may also explain the capacity of high-affinity hERG blockers to correct pentamidine-induced hERG trafficking defects."
35540224
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"Pentamidine induced long QT syndrome and block of hERG trafficking."
20547773
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"XREF_BIBR In addition, it has been found that Dofetilide and its analogues could correct pentamidine induced hERG trafficking defects."
34234416
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"Pentamidine induced long QT syndrome and block of hERG trafficking."
18462182
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"KURYSHEW YA, FICKER E, WANG L et al. : Pentamidine induced long QT syndrome and block of hERG trafficking."
15934850