IndraLab

Statements

RORC binds USP15. 6 / 6
1 | 5
sparser
"Interestingly, a catalytically inactive USP15 with a cysteine 298 to alanine mutation (C298A) ( xref ), had reduced interaction with RORγt ( xref ), suggesting important function of enzyme activity in RORγt-USP15 interaction."
27430721
biogrid
No evidence text available
27430721
sparser
"USP15 interacts with RORγt and removes ubiquitin from K446, and stimulates RORγt activity by enhancing coactivator SRC1 recruitment."
40821838
sparser
"USP15 interacts with RORγt, removes ubiquitin from K446, and enhances RORγt activity by promoting coactivator SRC1 recruitment."
40323348
sparser
"USP15 interacts with RORγt and deubiquitinates K446."
27430721
sparser
"We also confirmed the RORγt-USP15 interaction in differentiated Th17 cells ( xref )."
27430721