IndraLab

Statements



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"Furthermore, evidence from in vitro and in vivo studies revealed that depletion of USP27 inhibited HCC cell proliferation, invasion, metastasis and tumorigenesis, and that overexpression of SETD3 rescued this phenotype."

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"USP27X can also deubiquitinate and stabilize Snail1 when induced by TGF-beta and therefore promotes EMT and tumor metastasis [ 53 ] ."

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"Taken together, these results suggested that USP27 might promote hepatoma metastasis."

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"Although Cyclin E has been reported to involve in metastasis [XREF_BIBR], how USP27 promotes migration and metastasis also need further detailed exploration."

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"How does USP27 promote migration and metastasis?"