IndraLab

Statements


NFkappaB increases the amount of TNFAIP3. 6 / 6
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"TNFAIP3 expression is induced by NFkappaB 31."

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"TNFAIP3 expression is up-regulated by NF-kB activation, and acts in a negative feedback to control NF-kβ-dependent gene expression."

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"In our work, we found that NF-kappaB induced the expression of CXCL1, ICAM1 and TNFAIP3 after doxorubicin treatment only in a subset of tumors, suggesting that differences in responses may exist among tumor subtypes."

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"NF-kappaB signaling also induces TNFAIP3 expression, thus providing a further feedback loop that modifies inflammation."

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"NF-kappaB signaling induces transcription of the TNFAIP3 gene, encoding a ubiquitin modifying enzyme (also known as A20) that negatively regulates the NF-kappaB signaling pathway [XREF_BIBR - XREF_BIBR]."

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"Furthermore, persistent endothelial NF-kappaB activation by vFLIP induces expression of the NF-kappaB regulator A20 and TNFAIP3, which represses vFLIP induced NF-kappaB activation and augments IKK1 protein expression [XREF_BIBR]."