IndraLab

Statements

USP50 binds NLRP3. 8 / 8
3 | 5
biogrid
No evidence text available
28094437
sparser
"Co-immunoprecipitation experiments confirmed that USP50 physically interacts with NLRP3 (Fig.  xref C)."
40702108
sparser
"Co-IP showed USP50 bound NLRP3-WT, ΔNACHT, and ΔLRR, but not ΔPYD ( xref F), demonstrating that the PYD domain of NLRP3 is essential for USP50 binding."
41404189
biogrid
No evidence text available
38469295
biogrid
No evidence text available
40702108
sparser
"USP50 interacts with NLRP3 at the PYD domain."
41404189
sparser
"Our findings demonstrated that USP50 physically interacts with NLRP3, and its knockdown significantly increased NLRP3 ubiquitination levels."
40702108
sparser
"To confirm the endogenous interaction between USP50 and NLRP3, we performed IF and Co-IP assays."
41404189