IndraLab

Statements



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"HCQ has also been shown to significantly decrease cholinesterase activity, which can reverse the diminished production of saliva and gland hypofunction [ 43 ]."

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"Moreover, hydroxychloroquine has been reported to increase salivary flow rate by inhibiting glandular cholinesterase [XREF_BIBR], decrease inflammatory indices, that is, ESR and C reactive protein (CRP), and immunological abnormalities, that is, gamma-globulin, IgG, IgM, RF, anti-Ro, anti-La."

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"Cholinesterase activity was significantly elevated in the pSS patients and HCQ in clinically attainable levels decreased this cholinesterase activity in vitro."