IndraLab
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"Consistently, the pivotal role of modulation of sphingolipids in δTE-mediated A20 upregulation and anti-NF-κB is also supported by the observation that pharmacological blockage of de novo sphingolipids synthesis with myriocin, which prevents accumulation of dhCers, diminished δTE’s inhibitory effect on IκBα phosphorylation and induction of A20."