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A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

E3_Ub_ligase activates USP1. 1 / 1

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"USP1 is targeted for proteasomal degradation by the multi-subunit E3 ligase, APC/C Cdh1 in a cell cycle dependent manner [XREF_BIBR], so perhaps the decrease in USP1 is a consequence of the ability of PEITC to cause cell cycle arrest [XREF_BIBR, XREF_BIBR]."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...