
IndraLab
Statements
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"Primary ABCs are associated with mutations in oncogenes that are not detected in secondary ABCs, supporting a different pathogenic mechanism. xref The mesenchymal neoplastic nature of primary ABCs is characterised by genetic abnormalities in the osteoblast cadherin 11 gene ( CDH11 ) that results in the upregulation of the ubiquitin protease USP6 gene transcription."