IndraLab

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OTUB2 deubiquitinates RD21A. 7 / 7
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"Collectively, our findings demonstrate that OTU2 deubiquitinates RD21A, protecting it from PbE3-2-mediated degradation and thereby mitigating P. brassicae virulence."

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"OTU2 deubiquitinates RD21A, preventing its degradation via the 26S proteasome pathway."

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"OTU2 deubiquitinates RD21A and increases its stability."

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"The results showed that, compared with the control, the presence of OTU2 decreased the amount of RD21A‐FLAG labeled with Ub‐HA, suggesting that OTU2 deubiquitinates RD21A (Figure 3A)."

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"Together, these results suggest that OTU2 increases RD21A protein accumulation by deubiquitinating RD21A, thereby preventing its degradation via the 26S proteasome."

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"Furthermore, OTU2 deubiquitinates RD21A, promoting its accumulation and thereby enhancing A. thaliana resistance to P. brassicae."

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"Furthermore, OTU2 deubiquitinates RD21A both in vitro and in vivo, thereby increasing RD21A stability."