IndraLab

Statements


Modified USP15 increases the amount of RELA. 4 / 4
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"PDTC treatment significantly inhibited USP15 overexpression induced cell proliferation, apoptosis inhibition, and NF-kappaBp65 expression."

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"USP15 overexpression promoted NF-kappaBp65 expression through inhibition of its ubiquitination, whereas NF-kappaBp65 promoted USP15 expression as a positive regulator."

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"NF-kappaBp65 positively regulated USP15 expression, whereas USP15 overexpression promoted NF-kappaBp65 expression through deubiquitination of NF-kappaBp65 in MM cells."

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"USP15 overexpression promotes the expression of Bcl-2, Bcl-xL, Survivin, and NF-kappaBp65."