IndraLab

Statements


CYLD inhibits IL6. 6 / 6
| 6

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"CYLD overexpression clearly inhibited hypoxia induced synthesis and secretion of IL-6."

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"CYLD Enhances Severe Listeriosis by Impairing IL-6 and STAT3-Dependent Fibrin Production."

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"CYLD reduced IL-6, ROS production and killing of Lm in Listeria infected macrophages by impairing NF-kappaB activation."

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"In fact, CYLD overexpression significantly inhibited hypoxia triggered induction of IL-6 and IL-8."

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"Previously, we have shown that CYLD inhibits IL-6 production by macrophages, which in turn induces STAT3 dependent protective fibrin production by hepatocytes in listeriosis."

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"In fact, CYLD overexpression completely blocked hypoxia mediated induction of those inflammatory mediators and suppressed basal expression of some cytokines (IL-6, IL-8, IL1beta, IL-1F5, IL-1F8, and CXCL2)."