IndraLab

Statements

CYLD inhibits IL6. 9 / 9
| 9
reach
"CYLD overexpression clearly inhibited hypoxia induced synthesis and secretion of IL-6."
25071012
reach
"CYLD Enhances Severe Listeriosis by Impairing IL-6 and STAT3-Dependent Fibrin Production."
23825949
reach
"In fact, CYLD overexpression completely blocked hypoxia mediated induction of those inflammatory mediators and suppressed basal expression of some cytokines (IL-6, IL-8, IL1beta, IL-1F5, IL-1F8, and CXCL2)."
25071012
reach
"As expected, the mRNA expression levels of NF-κB down-streaming signals including Bcl-2, Mcl-1, MMP-9, Snail, NFKBIA, IL-1β, IL-6 and IL-18 were almost restored by CYLD knockdown in T24 and SW780 cell[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
36538852
reach
"Inhibition of CYLD in hepatocytes promoted IL-6/STAT3-mediated fibrin production and prevented the spread of L. monocytogenes (37)."
39958342
reach
"Previously, we have shown that CYLD inhibits IL-6 production by macrophages, which in turn induces STAT3 dependent protective fibrin production by hepatocytes in listeriosis."
28203236
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"CYLD reduced IL-6, ROS production and killing of Lm in Listeria infected macrophages by impairing NF-kappaB activation."
23825949
reach
"LPS treatment leads to increased release of TNF-α, IL-6, IL-1β and IFN-γ cytokines (Figs 3C and S2), however, CYLD-silenced MDMs produced higher IL-6 only as compared to control siRNA-treated MDMs and IL-6 level was unaffected when fludarabine was present in the cell culture (Fig 3C)."
37549179
reach
"In fact, CYLD overexpression significantly inhibited hypoxia triggered induction of IL-6 and IL-8."
25071012