IndraLab

Statements

KCNH2 activates sodium atom. 3 / 3
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"Whereas hERG channels are highly selective for K +, we have found that inactivated hERG channels allow Na + to permeate in the absence of K +."
16769794
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"Na (+) (o) inhibition of HERG current was relieved by physiological [K (+)] (o), while Na (+) (o) speeded recovery from inactivation similarly in the absence or presence of physiological [K (+)] (o)."
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"Since hERG inactivation resembles the C-type inactivation of Shaker channels, we proposed that the hERG channel allows Na + to permeate during the inactivation process."
16769794