IndraLab

Statements

USP15 activates PAH. 5 / 5
| 5
reach
"Taken together, our findings indicate that USP15 might promote PH progression in a YAP1/TAZ-dependent manner (Supplementary Fig. 3)."
36635430
reach
"We then investigated the preventative/reversal effect of USP15 knockdown in rats with MCT-induced PH."
36635430
reach
"Significantly less vascular muscularization was found after USP15 knockdown in both the preventative/reversal models of MCT-induced PH."
36635430
reach
"Collectively, these results demonstrated that downregulation of FUNDC1 induced by TNF-α led to the increased expression of USP15, which further stabilized and upregulated the protein level of Drp1.Cha[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
37871666
reach
"Therefore, our study aims to investigate whether USP15 promotes pulmonary vascular remodeling in PH via YAP1/TAZ signaling."
36635430