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This Service

A database built with INDRA combining content from numerous readers and databases. This page allows you to curate the loaded statements. For more information please see the manual.

This Project

INDRA is developed by indralabs, a part of the Harvard Medical School Laboratory of Systems Pharmacology.

This project, indra_db, is also developed by the indralab team. For more information on how we procure our sources, you can go here. This work was funded by ARO grant W911NF‐15‐1‐0544 under the DARPA Communicating with Computers program.

IndraLab

Statements

KCNMA1 inhibits ethanol. 2 / 2

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"In worms, the activation of the slo-1 BK channel by ethanol is a primary mechanism of the initial sensitivity to the intoxicating effects of ethanol, and loss of slo-1 causes resistance to ethanol."

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"RNAi of the additional positive controls, rab-3 and slo-1, reduced ethanol sensitivity as has been shown for loss-of-function mutants of these genes."

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Our Sources:

INDRA allows us to combine the results from a multitude of sources. In particular, the INDRA Database draws on the following...