IndraLab

Statements

Baicalein inhibits CASP1. 10 / 10
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"In agreement with our findings, baicalein, a traditional Chinese medicine, inhibited the NLRP3/caspase-1 pathway in a MPTP mouse PD model and subsequently attenuated dopaminergic neurodegeneration and[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"In hyperlipidemic pancreatitis, Baicalein modulates the miR-192-5p/TXNIP axis to inhibit the NLRP3/Caspase-1 pathway, thereby mitigating pyroptosis and inflammation [9]."
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"These findings indicated that baicalein inhibited the NLRP3/Caspase-1 pathway via the miR-192-5p axis and thus alleviated pyroptosis and inflammatory response.HP is a severe complication with extrapan[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Baicalein also inhibited the activation of caspase-1 and NLRP3 and decreased gasdermin D (GSDMD)-dependent pyroptosis."
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"Furthermore, we demonstrated that baicalein reduced MPP + -induced caspase 1 activation and IL-1β elevation in the infused SN."
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"Baicalein also inhibited NLRP3 and caspase-1 activation and suppressed gasdermin D (GSDMD)-dependent pyroptosis."
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"Notably, baicalein also inhibited NLRP3 activation and suppressed the cleavage of caspase-1 and GSDMD in the SNc as well as in mixed cultured glial cells."
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"These results suggested that baicalein inhibited the NLRP3/Caspase-1 pathway and alleviated cell pyroptosis and inflammatory response through the miR-192-5p/TXNIP axis.In summary, this study revealed [MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Baicalein also inhibited NLRP3 and caspase-1 activation and suppressed gasdermin D dependent pyroptosis."
32761175
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"Baicalein suppresses Coxsackievirus B3 replication by inhibiting caspase-1 and viral protease 2A."
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