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USP8 activates NRG. 2 / 2
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"Furthermore, UBPY-dependent deubiquitination has also been suggested to prevent degradation of the E3 ligase neuregulin receptor degradation pathway protein 1 (Nrdp1), which has a role in regulating s[MISSING/INVALID CREDENTIALS: limited to 200 char for Elsevier]"
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"Researchers have found that USP8 markedly enhanced the stability of neuregulin receptor degradation protein-1 (Nrdp1), which in turn inhibited the production of proinflammatory cytokines in toll like receptor triggered macrophages."
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